DegronMD - O00754(MAN2B1)

MAN2B1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S966Y	TCGA-AP-A059	UCEC	TCGA	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.0556
p.S966Y	DO41361	UCEC	ICGC	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.0556
p.W970L	TCGA-B5-A11E	UCEC	TCGA	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.1667
p.W970L	DO41644	UCEC	ICGC	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.1667
p.P987L	TCGA-DA-A1I0	SKCM	TCGA	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.1667
p.P987L	DO37719	SKCM	ICGC	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.1667
p.A988T	TCGA-EY-A1GI	UCEC	TCGA	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.1389
p.A988T	DO41211	UCEC	ICGC	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.1389
p.N973H	TCGA-IR-A3LI	CESC	TCGA	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.25
p.N973H	DO44400	CESC	ICGC	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.25
p.N989S	DO233259	GACA	ICGC	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.1111
p.P987T	DO228198	LICA	ICGC	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation rewiring degron network	0.1667
p.Q980K	DO229028	LICA	ICGC	PTPHQT	DEG_SCF_FBW7_1	976:981	Mutation altering degron motif	0.5833

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*NOTE: the Kaplan plots were collected from OncoLnc