DegronMD - O14529(CUX2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P1412H	TCGA-A5-A0G1	UCEC	TCGA	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.3056
p.P1412H	DO42472	UCEC	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.3056
p.V1410E	TCGA-AA-3966	COAD	TCGA	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.25
p.V1410E	DO10068	COAD	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.25
p.M1408I	TCGA-CG-5732	STAD	TCGA	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.1944
p.M1408I	DO38471	STAD	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.1944
p.S1409Y	TCGA-DU-6392	LGG	TCGA	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.2222
p.S1409Y	DO22237	LGG	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.2222
p.S1423F	TCGA-EB-A430	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.1667
p.S1423F	DO37906	SKCM	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.1667
p.A1427T	TCGA-EE-A2MM	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.0556
p.A1427T	DO222678	MELA	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.0556
p.A1427T	DO37770	SKCM	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.0556
p.S1421F	TCGA-EE-A3JA	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.2222
p.S1421F	DO47625	SKCM	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.2222
p.P1424S	TCGA-W3-A825	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.1389
p.P1424S	DO51272	SKCM	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.1389
p.P1424T	DO229053	LICA	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.1389
p.A1427S	DO229009	LICA	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.0556
p.P1404T	DO224563	LUSC	ICGC	VPSSS	DEG_SPOP_SBC_1	1413:1417	Mutation rewiring degron network	0.0833

Kaplan plot for CUX2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CUX2

UniProt ID: O14529

Entrez ID: 23316

Protein name: Homeobox protein cut-like 2 (Homeobox protein cux-2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CUX2 in