DegronMD - O14645(DNALI1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G64C	TCGA-AX-A1CE	UCEC	TCGA	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.25
p.G64C	DO42280	UCEC	ICGC	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.25
p.E44D	TCGA-AZ-4315	COAD	TCGA	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.0556
p.E44D	DO8842	COAD	ICGC	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.0556
p.V55A	TCGA-BR-6452	STAD	TCGA	STPCVPDP	DEG_COP1_1	54:61	Mutation altering degron motif	0.6936
p.V55A	DO38404	STAD	ICGC	STPCVPDP	DEG_COP1_1	54:61	Mutation altering degron motif	0.6936
p.K54Q	TCGA-EO-A22X	UCEC	TCGA	STPCVPDP	DEG_COP1_1	54:61	Mutation altering degron motif	0.6944
p.K54Q	DO43907	UCEC	ICGC	STPCVPDP	DEG_COP1_1	54:61	Mutation altering degron motif	0.6944
p.P67T	DO222492	COCA	ICGC	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.1667
p.S65L	DO220877	MELA	ICGC	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.2222
p.R51Q	SIDM00782	Colorectal Carcinoma	GDSC	STPCVPDP	DEG_COP1_1	54:61	Mutation substituting flanking lysine	0.3611
p.R51Q	ACH-000381	Colon/Colorectal Cancer	CCLE	STPCVPDP	DEG_COP1_1	54:61	Mutation substituting flanking lysine	0.3611
p.R51Q	T84	large intestine	COSMIC	STPCVPDP	DEG_COP1_1	54:61	Mutation substituting flanking lysine	0.3611
p.G64D	SIDM00140	Melanoma	GDSC	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.25
p.G64D	ACH-000968	Skin Cancer	CCLE	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.25
p.G64D	COLO-792	skin	COSMIC	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.25
p.K71M	ACH-000490	Cervical Cancer	CCLE	STPCVPDP	DEG_COP1_1	54:61	Mutation rewiring degron network	0.0556

Kaplan plot for DNALI1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

DNALI1

UniProt ID: O14645

Entrez ID: 7802

Protein name: Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for DNALI1 in