DegronMD - O14815(CAPN9)

CAPN9

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E30Q	TCGA-05-4397	LUAD	TCGA	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.0833
p.E30Q	DO25320	LUAD	ICGC	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.0833
p.S51N	TCGA-BG-A222	UCEC	TCGA	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.1667
p.S51N	DO42977	UCEC	ICGC	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.1667
p.L37R	TCGA-L5-A8NG	ESCA	TCGA	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.2778
p.A46S	DO229019	LICA	ICGC	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.3056
p.E30D	DO229015	LICA	ICGC	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.0833
p.F48S	ACH-000008	Skin Cancer	CCLE	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.25
p.F48S	ACH-000202	Colon/Colorectal Cancer	CCLE	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.25
p.F48S	ACH-001024	Skin Cancer	CCLE	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.25
p.F48S	ACH-002120	Skin Cancer	CCLE	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation rewiring degron network	0.25
p.G40V	ACH-001863	Bile Duct Cancer	CCLE	RGTLFED	LIG_APCC_ABBAyCdc20_2	39:45	Mutation altering degron motif	0.6421

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*NOTE: the Kaplan plots were collected from OncoLnc