DegronMD - O14827(RASGRF2)

RASGRF2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A775V	TCGA-2Y-A9H3	LIHC	TCGA	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1944
p.A775V	DO219525	LIHC	ICGC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1944
p.A775V	SIDM01145	Gastric Carcinoma	GDSC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1944
p.A775V	SIDM00383	Gastric Carcinoma	GDSC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1944
p.A775V	SIDM00164	Biliary Tract Carcinoma	GDSC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1944
p.S764N	TCGA-AX-A1C5	UCEC	TCGA	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.2778
p.S764N	DO41422	UCEC	ICGC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.2778
p.S776A	TCGA-AY-6197	COAD	TCGA	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation blocking phosphorylation signal	0.6111
p.S776A	DO9956	COAD	ICGC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation blocking phosphorylation signal	0.6111
p.S763A	TCGA-B5-A1MR	UCEC	TCGA	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.25
p.S763A	DO41758	UCEC	ICGC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.25
p.D759A	SIDM01007	T-Lymphoblastic Leukemia	GDSC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1389
p.D759A	ACH-002256	Leukemia	CCLE	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1389
p.D759A	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PTTTT	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc