DegronMD - O14830(PPEF2)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A742V	TCGA-05-4415	LUAD	TCGA	DSGCSS	DEG_SCF_TRCP1_1	744:749	Mutation rewiring degron network	0.2778
p.A742V	DO25747	LUAD	ICGC	DSGCSS	DEG_SCF_TRCP1_1	744:749	Mutation rewiring degron network	0.2778
p.P737Q	TCGA-ER-A19B	SKCM	TCGA	DSGCSS	DEG_SCF_TRCP1_1	744:749	Mutation rewiring degron network	0.1389
p.P737Q	DO47491	SKCM	ICGC	DSGCSS	DEG_SCF_TRCP1_1	744:749	Mutation rewiring degron network	0.1389
p.G746D	DO233867	GACA	ICGC	DSGCSS	DEG_SCF_TRCP1_1	744:749	Mutation altering degron motif	0.7198
p.P737T	DO229027	LICA	ICGC	DSGCSS	DEG_SCF_TRCP1_1	744:749	Mutation rewiring degron network	0.1389
p.G751A	DO46611	OV	ICGC	DSGCSS	DEG_SCF_TRCP1_1	744:749	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons