DegronMD - O14939(PLD2)

PLD2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S585Y	TCGA-AA-3812	COAD	TCGA	PKSTS	DEG_SPOP_SBC_1	583:587	Mutation altering degron motif	0.712
p.S585Y	DO10655	COAD	ICGC	PKSTS	DEG_SPOP_SBC_1	583:587	Mutation altering degron motif	0.712
p.Y580H	DO230309	COCA	ICGC	PKSTS	DEG_SPOP_SBC_1	583:587	Mutation blocking phosphorylation signal	0.6944
p.T577I	DO229003	COCA	ICGC	PKSTS	DEG_SPOP_SBC_1	583:587	Mutation rewiring degron network	0.1667
p.A589T	DO233276	GACA	ICGC	PKSTS	DEG_SPOP_SBC_1	583:587	Mutation rewiring degron network	0.2778
p.P576S	DO229052	LICA	ICGC	PKSTS	DEG_SPOP_SBC_1	583:587	Mutation rewiring degron network	0.1389
p.P576S	DO220913	MELA	ICGC	PKSTS	DEG_SPOP_SBC_1	583:587	Mutation rewiring degron network	0.1389
p.P593R	ACH-002926	Unknown	CCLE	PKSTS	DEG_SPOP_SBC_1	583:587	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc