DegronMD - O15056(SYNJ2)

SYNJ2

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D1435N	TCGA-2G-AAGV	TGCT	TCGA	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.25
p.G1440E	TCGA-CZ-4866	KIRC	TCGA	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation altering degron motif	0.7199
p.G1440E	DO16218	KIRC	ICGC	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation altering degron motif	0.7199
p.P1444H	TCGA-EE-A29E	SKCM	TCGA	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.3056
p.P1444H	DO37831	SKCM	ICGC	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.3056
p.W1429C	DO229028	LICA	ICGC	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.0833
p.D1438Y	DO229045	LICA	ICGC	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation altering degron motif	0.7325
p.L1430F	SIDM00291	Melanoma	GDSC	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.1111
p.L1430F	HMV-II	skin	COSMIC	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.1111
p.K1445R	SIDM00415	B-Cell Non-Hodgkin's Lymphoma	GDSC	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.2778
p.K1445R	ACH-001639	Leukemia	CCLE	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.2778
p.K1445R	ROS-50	haematopoietic and lymphoid tissue	COSMIC	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.2778
p.D1447H	ACH-000338	Lymphoma	CCLE	DSGTRS	DEG_SCF_TRCP1_1	1438:1443	Mutation rewiring degron network	0.2222

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc