DegronMD - O15211(RGL2)

RGL2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G555R	TCGA-57-1993	OV	TCGA	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.1389
p.G555R	DO30910	OV	ICGC	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.1389
p.W533R	TCGA-60-2698	LUSC	TCGA	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.0833
p.W533R	DO26469	LUSC	ICGC	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.0833
p.S553N	TCGA-A5-A1OF	UCEC	TCGA	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.1944
p.S553N	DO42568	UCEC	ICGC	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.1944
p.D557N	TCGA-AP-A1DV	UCEC	TCGA	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.0833
p.D557N	DO43186	UCEC	ICGC	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.0833
p.C549R	TCGA-BS-A0TA	UCEC	TCGA	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.3056
p.C549R	DO43298	UCEC	ICGC	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.3056
p.G541V	TCGA-HE-7130	KIRP	TCGA	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.3056
p.G541V	DO20776	KIRP	ICGC	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation rewiring degron network	0.3056
p.P545R	SIDM00292	Small Cell Lung Carcinoma	GDSC	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation altering degron motif	0.7512
p.P545R	ACH-002077	Lung Cancer	CCLE	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation altering degron motif	0.7512
p.P545R	LU-165	lung	COSMIC	VPTPLVS	DEG_SCF_FBW7_1	542:548	Mutation altering degron motif	0.7512

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*NOTE: the Kaplan plots were collected from OncoLnc