DegronMD - O15304(SIVA1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q15H	DO229038	LICA	ICGC	CPFADVAPL	DEG_SIAH_1	6:14	Mutation rewiring degron network	0.3056
p.R4W	DO230961	LUSC	ICGC	CPFADVAPL	DEG_SIAH_1	6:14	Mutation rewiring degron network	0.2778
p.R4W	DO224594	LUSC	ICGC	CPFADVAPL	DEG_SIAH_1	6:14	Mutation rewiring degron network	0.2778
p.P7R	SIDM02037	Pancreatic Carcinoma	GDSC	CPFADVAPL	DEG_SIAH_1	6:14	Mutation altering degron motif	0.7512
p.A12T	SIDM00416	B-Cell Non-Hodgkin's Lymphoma	GDSC	CPFADVAPL	DEG_SIAH_1	6:14	Mutation altering degron motif	0.6028
p.A12T	ACH-001703	Lymphoma	CCLE	CPFADVAPL	DEG_SIAH_1	6:14	Mutation altering degron motif	0.6028
p.A12T	VAL	haematopoietic and lymphoid tissue	COSMIC	CPFADVAPL	DEG_SIAH_1	6:14	Mutation altering degron motif	0.6028
p.P7S	SIDM00808	Burkitt's Lymphoma	GDSC	CPFADVAPL	DEG_SIAH_1	6:14	Mutation altering degron motif	0.6752
p.P7S	ACH-000707	Lymphoma	CCLE	CPFADVAPL	DEG_SIAH_1	6:14	Mutation altering degron motif	0.6752
p.L14P	ACH-000449	Sarcoma	CCLE	CPFADVAPL	DEG_SIAH_1	6:14	Mutation altering degron motif	0.7582
p.S5I	ACH-000702	Lymphoma	CCLE	CPFADVAPL	DEG_SIAH_1	6:14	Mutation blocking phosphorylation signal	0.75

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons