DegronMD - O15400(STX7)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R34I	TCGA-A5-A1OF	UCEC	TCGA	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1944
p.R34I	TCGA-AA-A00N	COAD	TCGA	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1944
p.R34I	TCGA-AP-A059	UCEC	TCGA	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1944
p.R34I	DO9876	COAD	ICGC	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1944
p.R34I	DO42568	UCEC	ICGC	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1944
p.R34I	DO41361	UCEC	ICGC	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1944
p.D44Y	TCGA-AJ-A3EL	UCEC	TCGA	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.6214
p.D44Y	DO41542	UCEC	ICGC	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.6214
p.I32T	TCGA-B5-A3FC	UCEC	TCGA	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1389
p.I32T	DO41871	UCEC	ICGC	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1389
p.L39F	DO8264	COAD	ICGC	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation altering degron motif	0.6981
p.E31A	SIDM00424	B-Cell Non-Hodgkin's Lymphoma	GDSC	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1111
p.E31A	ACH-001680	Lymphoma	CCLE	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1111
p.E31A	U-698-M	haematopoietic and lymphoid tissue	COSMIC	LGTPQDS	DEG_SCF_FBW7_1	39:45	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons