DegronMD - O43147(SGSM2)

SGSM2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P710L	TCGA-FS-A4F0	SKCM	TCGA	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation altering degron motif	0.7582
p.D718A	TCGA-HU-A4H4	STAD	TCGA	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.1111
p.V698M	DO233737	GACA	ICGC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.1667
p.G718C	DO229018	LICA	ICGC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.1111
p.D701N	DO45390	LUAD	ICGC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.25
p.P708R	DO46493	OV	ICGC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation altering degron motif	0.6401
p.S717P	DO229242	THCA	ICGC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.1389
p.E712D	SIDM00557	Neuroblastoma	GDSC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.2778
p.E712D	SIDM00291	Melanoma	GDSC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.2778
p.E712D	SIDM01413	Oral Cavity Carcinoma	GDSC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.2778
p.E712D	SIDM01451	Pancreatic Carcinoma	GDSC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.2778
p.E712D	SIDM01762	Esophageal Squamous Cell Carcinoma	GDSC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.2778
p.E712D	HMV-II	skin	COSMIC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.2778
p.E712D	KP-N-RT-BM-1	autonomic ganglia	COSMIC	DSGLPSS	DEG_SCF_TRCP1_1	704:710	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc