DegronMD - O43242(PSMD3)

PSMD3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E137D	TCGA-A5-A0G2	UCEC	TCGA	LLPFLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.3056
p.R128Q	TCGA-AX-A2HC	UCEC	TCGA	LLPFLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.25
p.R128Q	TCGA-XF-A8HD	BLCA	TCGA	LLPFLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.25
p.F134Y	DO233245	GACA	ICGC	LLPFLE	LIG_APCC_ABBA_1	131:136	Mutation altering degron motif	0.6417
p.L132F	DO222662	MELA	ICGC	LLPFLE	LIG_APCC_ABBA_1	131:136	Mutation altering degron motif	0.587
p.D140N	SIDM01016	T-Lymphoblastic Leukemia	GDSC	LLPFLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.2222
p.D140N	ACH-000995	Leukemia	CCLE	LLPFLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.2222
p.D140N	Jurkat	haematopoietic and lymphoid tissue	COSMIC	LLPFLE	LIG_APCC_ABBA_1	131:136	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc