DegronMD - O43247(TEX33)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K20N	DO228008	LAML	ICGC	AGTTT	DEG_SPOP_SBC_1	7:11	Mutation substituting flanking lysine	0.1944
p.T9A	DO220843	MELA	ICGC	AGTTT	DEG_SPOP_SBC_1	7:11	Mutation altering degron motif	0.7139
p.A7E	DO36386	READ	ICGC	AGTTT	DEG_SPOP_SBC_1	7:11	Mutation altering degron motif	0.7701
p.L3P	SIDM01259	B-Lymphoblastic Leukemia	GDSC	AGTTT	DEG_SPOP_SBC_1	7:11	Mutation substituting flanking lysine	0.3333
p.L3P	ACH-001669	Leukemia	CCLE	AGTTT	DEG_SPOP_SBC_1	7:11	Mutation substituting flanking lysine	0.3333
p.L3P	ACH-002238	Leukemia	CCLE	AGTTT	DEG_SPOP_SBC_1	7:11	Mutation substituting flanking lysine	0.3333
p.L3P	GR-ST	haematopoietic and lymphoid tissue	COSMIC	AGTTT	DEG_SPOP_SBC_1	7:11	Mutation substituting flanking lysine	0.3333
p.A11V	CCK-81	large intestine	COSMIC	AGTTT	DEG_SPOP_SBC_1	7:11	Mutation altering degron motif	0.6936

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons