DegronMD - O43251(RBFOX2)

RBFOX2

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P33S	TCGA-SQ-A6I6	PCPG	TCGA	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation altering degron motif	0.6752
p.G39E	DO222895	BTCA	ICGC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.2222
p.A20T	DO8119	COAD	ICGC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.1389
p.A20T	DO50142	STAD	ICGC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.1389
p.A20T	DO43186	UCEC	ICGC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.1389
p.A20T	SW1783	central nervous system	COSMIC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.1389
p.T40S	DO25535	LUAD	ICGC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.1944
p.L41P	DO220258	SARC	ICGC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.1667
p.P39S	DO219481	SKCM	ICGC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.2222
p.D19N	DO40810	UCEC	ICGC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.1111
p.D38Y	ACH-000436	Myeloma	CCLE	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.25
p.P29S	LNCaP-Clone-FGC	prostate	COSMIC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation altering degron motif	0.6752
p.V44L	CESS	haematopoietic and lymphoid tissue	COSMIC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.0833
p.P34L	CRO-AP3	NS	COSMIC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation altering degron motif	0.7582
p.V24L	CESS	haematopoietic and lymphoid tissue	COSMIC	TPDAMVQPF	DEG_SIAH_1	27:35	Mutation rewiring degron network	0.25

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc