DegronMD - O43390(HNRNPR)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D472N	TCGA-AD-6895	COAD	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1111
p.D472N	DO8938	COAD	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1111
p.Y461N	TCGA-AD-6895	COAD	TCGA	PPDY	ITCH	461:464	Mutation altering degron motif	0.7059
p.Y461N	DO8938	COAD	ICGC	PPDY	ITCH	461:464	Mutation altering degron motif	0.7059
p.D472E	TCGA-AP-A051	UCEC	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1111
p.D472E	DO42673	UCEC	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1111
p.R454H	TCGA-BR-8361	STAD	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1389
p.R454H	DO48032	STAD	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1389
p.R452W	TCGA-BS-A0UV	UCEC	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.0833
p.R452W	TCGA-HU-A4G8	STAD	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.0833
p.R452W	DO233798	GACA	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.0833
p.R452W	DO47819	STAD	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.0833
p.R452W	DO42793	UCEC	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.0833
p.Y467C	TCGA-CG-5721	STAD	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.25
p.Y467C	DO38192	STAD	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.25
p.G469D	TCGA-DM-A1DA	COAD	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1944
p.G469D	DO7852	COAD	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1944
p.G456W	TCGA-E2-A15J	BRCA	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1944
p.G456W	TCGA-YF-AA3L	BLCA	TCGA	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1944
p.G456W	DO51951	BLCA	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1944
p.G456W	DO4116	BRCA	ICGC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1944
p.S463A	Daudi	haematopoietic and lymphoid tissue	COSMIC	PPDY	ITCH	461:464	Mutation altering degron motif	0.7588
p.S463A	DND-41	haematopoietic and lymphoid tissue	COSMIC	PPDY	ITCH	461:464	Mutation altering degron motif	0.7588
p.S463A	OCI-AML5	haematopoietic and lymphoid tissue	COSMIC	PPDY	ITCH	461:464	Mutation altering degron motif	0.7588
p.D473Y	H9	haematopoietic and lymphoid tissue	COSMIC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.0833
p.R467H	P31-FUJ	haematopoietic and lymphoid tissue	COSMIC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.25
p.G454S	EJM	haematopoietic and lymphoid tissue	COSMIC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.1389
p.Q463E	S-117	soft tissue	COSMIC	PPDY	ITCH	461:464	Mutation altering degron motif	0.6744
p.Q463E	Daudi	haematopoietic and lymphoid tissue	COSMIC	PPDY	ITCH	461:464	Mutation altering degron motif	0.6744
p.S460F	MDA-MB-361	breast	COSMIC	PPDY	ITCH	461:464	Mutation rewiring degron network	0.3056

Kaplan plot for HNRNPR in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

HNRNPR

UniProt ID: O43390

Entrez ID: 10236

Protein name: Heterogeneous nuclear ribonucleoprotein R (hnRNP R)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for HNRNPR in