DegronMD - O43399(TPD52L2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G87E	TCGA-2W-A8YY	CESC	TCGA	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation altering degron motif	0.6087
p.S84F	TCGA-D8-A1XJ	BRCA	TCGA	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation altering degron motif	0.7982
p.S84F	SIDM00185	Melanoma	GDSC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation altering degron motif	0.7982
p.S84F	SIDM01650	Non-Cancerous	GDSC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation altering degron motif	0.7982
p.S84F	ACH-002354	Non-Cancerous	CCLE	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation altering degron motif	0.7982
p.A93T	DO233218	GACA	ICGC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation rewiring degron network	0.1667
p.Q92H	DO228952	LICA	ICGC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation rewiring degron network	0.1944
p.V77L	DO231788	LINC	ICGC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation rewiring degron network	0.2778
p.S73I	DO232224	PBCA	ICGC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation rewiring degron network	0.1667
p.Q95R	DO42745	UCEC	ICGC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation rewiring degron network	0.1111
p.S81G	WM793B	skin	COSMIC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation altering degron motif	0.6993
p.T89P	NCI-H1304	lung	COSMIC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation rewiring degron network	0.2778
p.S81R	HCC1954	breast	COSMIC	RRLGLSTLG	DEG_APCC_DBOX_1	79:87	Mutation altering degron motif	0.7427

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons