DegronMD - O43852(CALU)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K32R	TCGA-A2-A04Y	BRCA	TCGA	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.3056
p.K32R	DO2371	BRCA	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.3056
p.A23S	TCGA-B5-A11E	UCEC	TCGA	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.2778
p.A23S	DO41644	UCEC	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.2778
p.S19T	TCGA-CK-5913	COAD	TCGA	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.1667
p.S19T	DO8826	COAD	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.1667
p.P40S	TCGA-FW-A3R5	SKCM	TCGA	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.0833
p.P40S	DO37406	SKCM	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.0833
p.H38P	TCGA-XF-AAMX	BLCA	TCGA	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.1389
p.H38P	DO51939	BLCA	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.1389
p.I40T	DO234234	ESAD	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.0833
p.D39H	DO219648	KIRP	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.1111
p.F28L	DO23822	LUAD	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation altering degron motif	0.6981
p.P31A	DO221543	PACA	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation altering degron motif	0.7503
p.L18F	DO37406	SKCM	ICGC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.1389
p.V38F	ACH-000692	Head and Neck Cancer	CCLE	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.1389
p.N40I	ACH-000963	Colon/Colorectal Cancer	CCLE	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.0833
p.N40I	CCK-81	large intestine	COSMIC	KDRVHHE	LIG_APCC_ABBAyCdc20_2	25:31	Mutation rewiring degron network	0.0833

Kaplan plot for CALU in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CALU

UniProt ID: O43852

Entrez ID: 813

Protein name: Calumenin (Crocalbin) (IEF SSP 9302)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CALU in