DegronMD - O43933(PEX1)

PEX1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E232K	TCGA-19-5956	GBM	TCGA	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.1944
p.E232K	DO13863	GBM	ICGC	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.1944
p.G250E	TCGA-A2-A0YK	BRCA	TCGA	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.0833
p.G250E	DO2836	BRCA	ICGC	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.0833
p.I235S	TCGA-B5-A11N	UCEC	TCGA	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.2778
p.I235S	DO41458	UCEC	ICGC	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.2778
p.V242A	TCGA-DI-A1BU	UCEC	TCGA	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.3056
p.V242A	DO42023	UCEC	ICGC	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.3056
p.S239F	DO220877	MELA	ICGC	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation altering degron motif	0.7982
p.S239F	DO220891	MELA	ICGC	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation altering degron motif	0.7982
p.S239F	DO37404	SKCM	ICGC	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation altering degron motif	0.7982
p.S228F	DO222875	MELA	ICGC	VDSSS	DEG_SPOP_SBC_1	237:241	Mutation rewiring degron network	0.0833

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc