DegronMD - O60239(SH3BP5)

SH3BP5

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R165G	TCGA-CM-6171	COAD	TCGA	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.1667
p.S155A	DO12382	GBM	ICGC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation altering degron motif	0.7588
p.V154L	DO13114	GBM	ICGC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation altering degron motif	0.6765
p.D147Y	DO232224	PBCA	ICGC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.2222
p.D147G	DO229253	THCA	ICGC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.2222
p.T163I	SIDM01945	Colorectal Carcinoma	GDSC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.2222
p.D146E	SIDM01124	Non-Small Cell Lung Carcinoma	GDSC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.1944
p.D146E	ACH-000945	Lung Cancer	CCLE	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.1944
p.D146E	NCI-H650	lung	COSMIC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.1944
p.R149W	SIDM01088	Endometrial Carcinoma	GDSC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.2778
p.S151T	IM-95	stomach	COSMIC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation altering degron motif	0.7116
p.E146K	ESS-1	endometrium	COSMIC	FDSAWQEML	DEG_MDM2_SWIB_1	151:159	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc