DegronMD - O60422(ONECUT3)

ONECUT3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T446A	TCGA-B5-A1MX	UCEC	TCGA	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.0833
p.T446A	DO41999	UCEC	ICGC	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.0833
p.R427H	TCGA-CM-4746	COAD	TCGA	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.1667
p.R427H	DO7882	COAD	ICGC	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.1667
p.I430V	TCGA-WZ-A8D5	TGCT	TCGA	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.25
p.M443K	DO228926	LICA	ICGC	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.1667
p.F433L	DO50720	ORCA	ICGC	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation altering degron motif	0.587
p.V445I	DO232519	PBCA	ICGC	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.1111
p.T428M	DO229264	THCA	ICGC	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.1944
p.R438Q	DO229216	THCA	ICGC	FKENK	DEG_APCC_KENBOX_2	433:437	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc