DegronMD - O60508(CDC40)

CDC40

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D190H	TCGA-56-7731	LUSC	TCGA	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation rewiring degron network	0.1944
p.D190H	DO45527	LUSC	ICGC	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation rewiring degron network	0.1944
p.D185Y	TCGA-CN-4741	HNSC	TCGA	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation altering degron motif	0.6214
p.D185Y	DO14313	HNSC	ICGC	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation altering degron motif	0.6214
p.K180T	DO234363	ESAD	ICGC	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation rewiring degron network	0.3056
p.D190Y	DO229029	LICA	ICGC	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation rewiring degron network	0.1944
p.D190Y	SIDM00388	B-Cell Non-Hodgkin's Lymphoma	GDSC	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation rewiring degron network	0.1944
p.D190Y	ACH-002272	Lymphoma	CCLE	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation rewiring degron network	0.1944
p.D190Y	MHH-PREB-1	haematopoietic and lymphoid tissue	COSMIC	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation rewiring degron network	0.1944
p.Q172R	DO50929	LICA	ICGC	FKEND	DEG_APCC_KENBOX_2	181:185	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc