DegronMD - O60704(TPST2)

TPST2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P337T	TCGA-AA-3821	COAD	TCGA	PPNY	ITCH	331:334	Mutation rewiring degron network	0.25
p.P337T	DO9314	COAD	ICGC	PPNY	ITCH	331:334	Mutation rewiring degron network	0.25
p.D338N	TCGA-DK-A2I4	BLCA	TCGA	PPNY	ITCH	331:334	Mutation rewiring degron network	0.2222
p.D338N	DO465	BLCA	ICGC	PPNY	ITCH	331:334	Mutation rewiring degron network	0.2222
p.A321V	TCGA-V5-AASW	ESCA	TCGA	PPNY	ITCH	331:334	Mutation rewiring degron network	0.0556
p.N330T	DO233856	GACA	ICGC	PPNY	ITCH	331:334	Mutation rewiring degron network	0.3056
p.P332L	SIDM00088	Prostate Carcinoma	GDSC	PPNY	ITCH	331:334	Mutation altering degron motif	0.7582
p.P332L	ACH-000090	Prostate Cancer	CCLE	PPNY	ITCH	331:334	Mutation altering degron motif	0.7582
p.P332L	PC-3	prostate	COSMIC	PPNY	ITCH	331:334	Mutation altering degron motif	0.7582
p.N336I	SIDM00711	Squamous Cell Lung Carcinoma	GDSC	PPNY	ITCH	331:334	Mutation rewiring degron network	0.2778
p.N336I	ACH-000727	Lung Cancer	CCLE	PPNY	ITCH	331:334	Mutation rewiring degron network	0.2778
p.N336I	NCI-H2066	lung	COSMIC	PPNY	ITCH	331:334	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc