DegronMD - O60806(TBX19)

TBX19

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S329F	TCGA-BF-AAP2	SKCM	TCGA	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation altering degron motif	0.6871
p.S329F	DO219466	SKCM	ICGC	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation altering degron motif	0.6871
p.S335G	TCGA-BR-8060	STAD	TCGA	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation altering degron motif	0.6993
p.S335G	DO38205	STAD	ICGC	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation altering degron motif	0.6993
p.S327F	TCGA-FW-A3R5	SKCM	TCGA	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation rewiring degron network	0.3056
p.S327F	DO37406	SKCM	ICGC	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation rewiring degron network	0.3056
p.S335I	DO222404	BTCA	ICGC	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation altering degron motif	0.7341
p.P332S	DO229502	SKCA	ICGC	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation altering degron motif	0.6752
p.N343Y	SIDM00962	Chronic Myelogenous Leukemia	GDSC	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation rewiring degron network	0.1111
p.N343Y	BV-173	haematopoietic and lymphoid tissue	COSMIC	LSSTPHAS	DEG_SCF_FBW7_1	328:335	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc