DegronMD - O60884(DNAJA2)

DNAJA2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R230I	TCGA-AG-A002	READ	TCGA	LEVHVD	LIG_APCC_ABBA_1	217:222	Mutation rewiring degron network	0.1111
p.V219D	TCGA-BR-6452	STAD	TCGA	LEVHVD	LIG_APCC_ABBA_1	217:222	Mutation altering degron motif	0.7785
p.V219D	DO38404	STAD	ICGC	LEVHVD	LIG_APCC_ABBA_1	217:222	Mutation altering degron motif	0.7785
p.K209Q	TCGA-IN-A6RL	STAD	TCGA	LEVHVD	LIG_APCC_ABBA_1	217:222	Mutation substituting flanking lysine	0.2222
p.K209Q	DO51738	STAD	ICGC	LEVHVD	LIG_APCC_ABBA_1	217:222	Mutation substituting flanking lysine	0.2222
p.D222E	DO229045	LICA	ICGC	LEVHVD	LIG_APCC_ABBA_1	217:222	Mutation altering degron motif	0.5647
p.K209R	SIDM01951	Colorectal Carcinoma	GDSC	LEVHVD	LIG_APCC_ABBA_1	217:222	Mutation substituting flanking lysine	0.2222
p.K208N	ACH-000954	Endometrial/Uterine Cancer	CCLE	LEVHVD	LIG_APCC_ABBA_1	217:222	Mutation substituting flanking lysine	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc