DegronMD - O60907(TBL1X)

TBL1X

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V182I	TCGA-12-0692	GBM	TCGA	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.2222
p.A170S	TCGA-55-A492	LUAD	TCGA	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.2222
p.A164V	TCGA-5M-AAT6	COAD	TCGA	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.0556
p.S188L	TCGA-EO-A22U	UCEC	TCGA	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.0556
p.T175A	DO6466	CLLE	ICGC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation altering degron motif	0.7139
p.R178Q	DO10694	COAD	ICGC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation altering degron motif	0.7329
p.G179V	DO229019	LICA	ICGC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.3056
p.G179V	DO229028	LICA	ICGC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.3056
p.I186M	DO231602	LINC	ICGC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.1111
p.R178W	DO35442	PACA	ICGC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation altering degron motif	0.8634
p.L177I	DO37782	SKCM	ICGC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation altering degron motif	0.7174
p.H180R	DO42472	UCEC	ICGC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.2778
p.A165V	SIDM00951	T-Lymphoblastic Leukemia	GDSC	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.0833
p.S183P	ACH-000993	Endometrial/Uterine Cancer	CCLE	AATTT	DEG_SPOP_SBC_1	174:178	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc