DegronMD - O60909(B4GALT2)

B4GALT2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P146L	TCGA-55-A4DF	LUAD	TCGA	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.2778
p.R149W	TCGA-AX-A1C4	UCEC	TCGA	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.1944
p.R149W	SIDM00399	Head and Neck Carcinoma	GDSC	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.1944
p.R149W	SCC90	upper aerodigestive tract	COSMIC	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.1944
p.R149L	TCGA-FS-A1Z0	SKCM	TCGA	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.1944
p.T135I	DO231827	LINC	ICGC	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.2778
p.L138V	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation altering degron motif	0.6765
p.L138V	NCI-H1155	lung	COSMIC	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation altering degron motif	0.6765
p.T140I	ACH-000280	Ovarian Cancer	CCLE	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation altering degron motif	0.7078
p.A146V	ACH-002391	Head and Neck Cancer	CCLE	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.2778
p.A146V	UDSCC2	upper aerodigestive tract	COSMIC	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.2778
p.L129F	SNU-175	large intestine	COSMIC	PDCTPAQT	DEG_SCF_FBW7_1	137:144	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc