DegronMD - O75023(LILRB5)

LILRB5

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P438H	TCGA-21-1082	LUSC	TCGA	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation altering degron motif	0.7694
p.P438H	DO26463	LUSC	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation altering degron motif	0.7694
p.D423Y	TCGA-DX-A8BV	SARC	TCGA	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.0556
p.D423Y	DO220066	SARC	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.0556
p.L425P	DO8264	COAD	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1111
p.R443P	DO229003	COCA	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1944
p.R443P	DO229005	COCA	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1944
p.R443P	DO231102	LUSC	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1944
p.G430C	DO228542	GACA	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.25
p.T444N	DO232666	PBCA	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1667
p.L425I	DO36881	READ	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1111
p.A428D	DO229216	THCA	ICGC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1944
p.P444L	ACH-000969	Colon/Colorectal Cancer	CCLE	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1667
p.A446S	AU565	breast	COSMIC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.1111
p.T432I	LN-18	central nervous system	COSMIC	PTPGPE	DEG_SCF_FBW7_2	433:438	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc