DegronMD - O75106(AOC2)

AOC2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.I123V	TCGA-33-4566	LUSC	TCGA	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.5965
p.I123V	DO26790	LUSC	ICGC	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.5965
p.I123T	TCGA-A3-3370	KIRC	TCGA	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.5966
p.I123T	DO18452	KIRC	ICGC	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.5966
p.P114L	TCGA-CN-5373	HNSC	TCGA	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation rewiring degron network	0.25
p.P114L	DO16101	HNSC	ICGC	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation rewiring degron network	0.25
p.V124I	TCGA-IB-7651	PAAD	TCGA	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.5965
p.V124I	DO46657	PAAD	ICGC	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.5965
p.R118W	TCGA-L5-A4OI	ESCA	TCGA	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.8634
p.E119D	DO229015	LICA	ICGC	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.5647
p.A122S	DO229026	LICA	ICGC	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.6477
p.R118Q	SIDM00045	Gastric Carcinoma	GDSC	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.7329
p.R118Q	ACH-002141	Gastric Cancer	CCLE	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.7329
p.R118Q	HSC-39	stomach	COSMIC	AREALAIVL	DEG_APCC_DBOX_1	117:125	Mutation altering degron motif	0.7329

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*NOTE: the Kaplan plots were collected from OncoLnc