DegronMD - O75154(RAB11FIP3)

RAB11FIP3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G412C	TCGA-55-A490	LUAD	TCGA	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.1389
p.G412C	DO24596	LUAD	ICGC	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.1389
p.R426Q	TCGA-D6-6515	HNSC	TCGA	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.2778
p.K425N	TCGA-DX-A6YT	SARC	TCGA	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.3056
p.R426W	TCGA-EO-A3B0	UCEC	TCGA	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.2778
p.V419I	DO227906	COCA	ICGC	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation altering degron motif	0.7076
p.A427V	DO234219	ESAD	ICGC	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.25
p.D424V	DO52163	LIHC	ICGC	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation altering degron motif	0.7785
p.S422I	DO50679	ORCA	ICGC	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation altering degron motif	0.623
p.A417T	SIDM01090	Colorectal Carcinoma	GDSC	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.2778
p.A417T	ACH-000943	Colon/Colorectal Cancer	CCLE	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.2778
p.A417T	RKO	large intestine	COSMIC	LTPSPT	DEG_SCF_FBW7_1	419:424	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc