DegronMD - O75449(KATNA1)

KATNA1

UniProt ID: O75449

Entrez ID: 11104

Protein name: Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin)

External links: UniprotKB HGNC RefSeq COSMIC

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GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D89E	TCGA-12-0778	GBM	TCGA	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.1944
p.D89E	DO11411	GBM	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.1944
p.E94D	TCGA-4Z-AA7O	BLCA	TCGA	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.0556
p.E94D	DO51865	BLCA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.0556
p.E94Q	TCGA-4Z-AA7W	BLCA	TCGA	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.0556
p.E94Q	DO218984	BLCA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.0556
p.E94Q	ACH-001699	Head and Neck Cancer	CCLE	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.0556
p.E94G	TCGA-HU-A4GT	STAD	TCGA	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.0556
p.E94G	DO48020	STAD	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.0556
p.P82L	TCGA-YD-A89C	SKCM	TCGA	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation altering degron motif	0.7582
p.P82L	DO219501	SKCM	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation altering degron motif	0.7582
p.D79H	TCGA-ZF-AA54	BLCA	TCGA	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation altering degron motif	0.7688
p.D79H	DO219098	BLCA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation altering degron motif	0.7688
p.H88N	DO228976	LICA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.2222
p.A85E	DO229034	LICA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.3056
p.S75I	DO233295	NACA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.2778
p.A86T	DO233299	NACA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.2778
p.H88R	DO229253	THCA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.2222
p.A85S	DO229232	THCA	ICGC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.3056
p.A85V	SIDM00379	Glioma	GDSC	KLDSTPLK	DEG_SCF_SKP2-CKS1_1	77:84	Mutation rewiring degron network	0.3056

Kaplan plot for KATNA1 in

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*NOTE: the Kaplan plots were collected from OncoLnc