DegronMD - O75459(PAGE1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R10L	TCGA-A5-A1OG	UCEC	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.2778
p.R10L	DO43731	UCEC	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.2778
p.R11C	TCGA-A8-A07C	BRCA	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.3056
p.R11C	DO4713	BRCA	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.3056
p.R11H	TCGA-AX-A2HC	UCEC	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.3056
p.R11H	DO233767	GACA	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.3056
p.R11H	DO41572	UCEC	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.3056
p.Y9H	TCGA-BR-4201	STAD	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation blocking phosphorylation signal	0.6944
p.Y9H	DO38707	STAD	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation blocking phosphorylation signal	0.6944
p.L4V	TCGA-D8-A1JJ	BRCA	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.1111
p.L4V	DO4599	BRCA	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.1111
p.G2S	TCGA-D8-A1X9	BRCA	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.0556
p.G2S	DO5472	BRCA	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.0556
p.I8M	TCGA-EK-A2IP	CESC	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.2222
p.I8M	DO48978	CESC	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.2222
p.L7V	TCGA-IB-7646	PAAD	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.1944
p.L7V	DO46649	PAAD	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.1944
p.Y9N	TCGA-R8-A73M	LGG	TCGA	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation blocking phosphorylation signal	0.6944
p.Y9N	DO48591	LGG	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation blocking phosphorylation signal	0.6944
p.M14T	DO228207	LICA	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation altering degron motif	0.6312
p.D25A	DO48732	LIRI	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.1389
p.R10W	DO222644	MELA	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation rewiring degron network	0.2778
p.M14I	DO51050	PRAD	ICGC	RPMIYVE	LIG_APCC_ABBAyCdc20_2	12:18	Mutation altering degron motif	0.6507

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DegronMD: protein-targeted degradation, mutation and drug response to degrons

PAGE1

UniProt ID: O75459

Entrez ID: 8712

Protein name: P antigen family member 1 (PAGE-1) (AL5) (G antigen 9) (GAGE-9) (G antigen family B member 1) (Prostate-associated gene 1 protein)

External links: UniprotKB HGNC RefSeq COSMIC

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