DegronMD - O75478(TADA2A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R360Q	TCGA-32-2494	GBM	TCGA	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.0556
p.R360Q	TCGA-A5-A0G1	UCEC	TCGA	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.0556
p.R360Q	DO11998	GBM	ICGC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.0556
p.R360Q	DO42472	UCEC	ICGC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.0556
p.R359K	TCGA-B5-A11R	UCEC	TCGA	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.0833
p.R359K	DO43787	UCEC	ICGC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.0833
p.R338C	TCGA-EE-A2GJ	SKCM	TCGA	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.1667
p.R338C	DO37746	SKCM	ICGC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.1667
p.G358D	TCGA-XF-AAMX	BLCA	TCGA	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.1111
p.G358D	DO51939	BLCA	ICGC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.1111
p.W336L	DO1094	BRCA	ICGC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.1111
p.S355L	DO233764	GACA	ICGC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.1944
p.P349S	DO229465	SKCA	ICGC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation altering degron motif	0.5641
p.I351M	SIDM00068	Colorectal Carcinoma	GDSC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.3056
p.I351M	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.3056
p.I351M	SIDM01173	Rhabdomyosarcoma	GDSC	DSGLSPS	DEG_SCF_TRCP1_1	344:350	Mutation rewiring degron network	0.3056

Kaplan plot for TADA2A in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

TADA2A

UniProt ID: O75478

Entrez ID: 6871

Protein name: Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for TADA2A in