DegronMD - O75643(SNRNP200)

SNRNP200

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R406L	TCGA-55-8301	LUAD	TCGA	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation altering degron motif	0.7316
p.R406L	DO24682	LUAD	ICGC	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation altering degron motif	0.7316
p.E401K	TCGA-86-8673	LUAD	TCGA	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation rewiring degron network	0.2778
p.E401K	DO26260	LUAD	ICGC	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation rewiring degron network	0.2778
p.E412D	TCGA-DQ-5629	HNSC	TCGA	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation altering degron motif	0.5647
p.E412D	DO15270	HNSC	ICGC	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation altering degron motif	0.5647
p.R406Q	SIDM00839	Colorectal Carcinoma	GDSC	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation altering degron motif	0.6218
p.R406Q	ACH-000950	Colon/Colorectal Cancer	CCLE	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation altering degron motif	0.6218
p.R406Q	LoVo	large intestine	COSMIC	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation altering degron motif	0.6218
p.Q398R	ACH-000593	Bladder Cancer	CCLE	LAPRQVLDLEDLVF	DEG_ODPH_VHL_1	403:416	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc