DegronMD - O75874(IDH1)

IDH1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P33S	TCGA-AA-3949	COAD	TCGA	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6752
p.P33S	TCGA-BF-A1PX	SKCM	TCGA	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6752
p.P33S	TCGA-EE-A3JI	SKCM	TCGA	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6752
p.P33S	TCGA-W3-AA1V	SKCM	TCGA	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6752
p.P33S	DO7798	COAD	ICGC	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6752
p.P33S	DO47268	SKCM	ICGC	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6752
p.P33S	DO51276	SKCM	ICGC	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6752
p.P33S	DO51236	SKCM	ICGC	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6752
p.V35M	TCGA-AD-5900	COAD	TCGA	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6097
p.V35M	DO8514	COAD	ICGC	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.6097
p.D43H	TCGA-K4-A83P	BLCA	TCGA	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation rewiring degron network	0.1389
p.D43H	DO49787	BLCA	ICGC	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation rewiring degron network	0.1389
p.F32V	SIDM00861	Ovarian Carcinoma	GDSC	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation altering degron motif	0.5957
p.D38N	ACH-000279	Bone Cancer	CCLE	IFPYVE	LIG_APCC_ABBA_1	31:36	Mutation rewiring degron network	0.2778

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc