DegronMD - O75899(GABBR2)

GABBR2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P820T	TCGA-91-8496	LUAD	TCGA	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation altering degron motif	0.7031
p.P820T	DO45379	LUAD	ICGC	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation altering degron motif	0.7031
p.E821Q	TCGA-IR-A3LH	CESC	TCGA	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation altering degron motif	0.5633
p.E821Q	DO44381	CESC	ICGC	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation altering degron motif	0.5633
p.I826T	DO222455	ESCA	ICGC	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.25
p.E811D	DO50780	LIRI	ICGC	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.1944
p.T824I	SIDM01169	Ovarian Carcinoma	GDSC	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.3056
p.T824I	ACH-000885	Ovarian Cancer	CCLE	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.3056
p.T824I	TOV-21G	ovary	COSMIC	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.3056
p.D808Y	SIDM00193	Colorectal Carcinoma	GDSC	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.1111
p.D808Y	ACH-000991	Colon/Colorectal Cancer	CCLE	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.1111
p.D808Y	SNU-81	large intestine	COSMIC	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.1111
p.E833K	ACH-001061	Colon/Colorectal Cancer	CCLE	LQDTPEKT	DEG_SCF_FBW7_1	816:823	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc