DegronMD - O75937(DNAJC8)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R78W	TCGA-AA-A010	COAD	TCGA	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation rewiring degron network	0.2222
p.R78W	TCGA-BR-8591	STAD	TCGA	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation rewiring degron network	0.2222
p.R78W	DO232761	PBCA	ICGC	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation rewiring degron network	0.2222
p.R78W	DO47973	STAD	ICGC	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation rewiring degron network	0.2222
p.I82T	TCGA-BR-8059	STAD	TCGA	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation altering degron motif	0.7078
p.I82T	DO38443	STAD	ICGC	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation altering degron motif	0.7078
p.K88T	TCGA-CA-6717	COAD	TCGA	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation rewiring degron network	0.3056
p.K88T	DO8264	COAD	ICGC	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation rewiring degron network	0.3056
p.P86S	TCGA-EE-A3AC	SKCM	TCGA	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation altering degron motif	0.5641
p.P86S	DO37631	SKCM	ICGC	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation altering degron motif	0.5641
p.R76S	TCGA-NH-A5IV	COAD	TCGA	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation rewiring degron network	0.1667
p.R76S	DO49095	COAD	ICGC	ILVHPD	LIG_APCC_ABBA_1	82:87	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons