DegronMD - O75953(DNAJB5)

DNAJB5

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E183K	TCGA-AA-A01T	COAD	TCGA	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation altering degron motif	0.7022
p.G189S	TCGA-AG-3742	READ	TCGA	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.1667
p.L186P	TCGA-AP-A1DK	UCEC	TCGA	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.25
p.E183Q	TCGA-CG-4437	STAD	TCGA	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation altering degron motif	0.6744
p.G189R	TCGA-EB-A3Y7	SKCM	TCGA	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.1667
p.E169D	DO227976	COCA	ICGC	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.1667
p.R176L	DO229008	LICA	ICGC	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation altering degron motif	0.8428
p.G190S	SIDM01016	T-Lymphoblastic Leukemia	GDSC	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.1389
p.G190S	SIDM01263	T-Lymphoblastic Leukemia	GDSC	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.1389
p.G190S	Jurkat	haematopoietic and lymphoid tissue	COSMIC	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.1389
p.S170I	SIDM00980	Gastric Carcinoma	GDSC	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.1944
p.S170I	23132-87	stomach	COSMIC	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation rewiring degron network	0.1944
p.S177P	MFE-319	endometrium	COSMIC	LRVSLEEIY	DEG_APCC_DBOX_1	175:183	Mutation altering degron motif	0.6752

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*NOTE: the Kaplan plots were collected from OncoLnc