DegronMD - O94952(FBXO21)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D627A	TCGA-21-A5DI	LUSC	TCGA	KKENI	DEG_APCC_KENBOX_2	622:626	Mutation rewiring degron network	0.3056
p.V615M	TCGA-99-8028	LUAD	TCGA	KKENI	DEG_APCC_KENBOX_2	622:626	Mutation rewiring degron network	0.1389
p.N625S	TCGA-AP-A1DV	UCEC	TCGA	KKENI	DEG_APCC_KENBOX_2	622:626	Mutation altering degron motif	0.7069
p.E624K	TCGA-BH-A0HP	BRCA	TCGA	KKENI	DEG_APCC_KENBOX_2	622:626	Mutation altering degron motif	0.7022
p.E617K	DO1755	BRCA	ICGC	KKENI	DEG_APCC_KENBOX_2	622:626	Mutation rewiring degron network	0.1944
p.D620A	DO45455	LUSC	ICGC	KKENI	DEG_APCC_KENBOX_2	622:626	Mutation rewiring degron network	0.2778
p.K615N	DO227579	ORCA	ICGC	KKENI	DEG_APCC_KENBOX_2	622:626	Mutation rewiring degron network	0.1389
p.N618S	DO43186	UCEC	ICGC	KKENI	DEG_APCC_KENBOX_2	622:626	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons