DegronMD - O94967(WDR47)

WDR47

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A288V	TCGA-06-5416	GBM	TCGA	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation altering degron motif	0.6936
p.T292I	TCGA-14-0867	GBM	TCGA	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation blocking phosphorylation signal	0.6944
p.L291V	TCGA-BH-A1FG	BRCA	TCGA	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation rewiring degron network	0.2778
p.L294R	TCGA-CA-6717	COAD	TCGA	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation rewiring degron network	0.1944
p.H275N	TCGA-MV-A51V	BLCA	TCGA	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation rewiring degron network	0.1111
p.V276F	TCGA-NC-A5HR	LUSC	TCGA	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation rewiring degron network	0.1389
p.Q275R	DO52318	LIHC	ICGC	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation rewiring degron network	0.1111
p.S284F	DO37487	SKCM	ICGC	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation altering degron motif	0.7982
p.R283H	DO47981	STAD	ICGC	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation altering degron motif	0.8244
p.R283H	DO52409	UCEC	ICGC	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation altering degron motif	0.8244
p.R283H	DO43891	UCEC	ICGC	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation altering degron motif	0.8244
p.L289F	IGROV-1	ovary	COSMIC	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation altering degron motif	0.6981
p.L289F	NCI-H510A	lung	COSMIC	LLTPLIS	DEG_SCF_FBW7_1	283:289	Mutation altering degron motif	0.6981

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*NOTE: the Kaplan plots were collected from OncoLnc