DegronMD - O95070(YIF1A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A19V	TCGA-04-1331	OV	TCGA	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.1111
p.A19V	DO28119	OV	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.1111
p.A19V	DO41871	UCEC	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.1111
p.A45S	TCGA-61-1914	OV	TCGA	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.1111
p.A45S	DO28105	OV	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.1111
p.G38R	TCGA-AA-3492	COAD	TCGA	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.3056
p.G38R	DO8224	COAD	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.3056
p.G38R	SIDM01007	T-Lymphoblastic Leukemia	GDSC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.3056
p.G38R	SIDM00079	Ovarian Carcinoma	GDSC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.3056
p.G38R	ACH-000811	Ovarian Cancer	CCLE	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.3056
p.G38R	ACH-002256	Leukemia	CCLE	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.3056
p.G38R	SK-OV-3	ovary	COSMIC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.3056
p.G38R	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.3056
p.G31S	TCGA-BH-A0HQ	BRCA	TCGA	DDTSGGYSSQP	CBL_PTK	27:37	Mutation altering degron motif	0.5882
p.G31S	DO3082	BRCA	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation altering degron motif	0.5882
p.Y40S	DO48438	BLCA	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.25
p.A42T	DO884	BOCA	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.1944
p.D27N	DO222864	COCA	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation altering degron motif	0.5821
p.V18M	DO233867	GACA	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.0833
p.T43K	DO229037	LICA	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.1667
p.D46Y	DO232761	PBCA	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.0833
p.G46W	DO37778	SKCM	ICGC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.0833
p.I31M	RKO	large intestine	COSMIC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation altering degron motif	0.7618
p.A39D	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	DDTSGGYSSQP	CBL_PTK	27:37	Mutation rewiring degron network	0.2778

Kaplan plot for YIF1A in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

YIF1A

UniProt ID: O95070

Entrez ID: 10897

Protein name: Protein YIF1A (54TMp) (YIP1-interacting factor homolog A)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for YIF1A in