NDUFC2
UniProt ID: O95298
Entrez ID: 4718
Protein name: NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate elect...
FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. {ECO:0000269|PubMed:27626371, ECO:0000269|PubMed:32969598}.
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GO - Biological processes (BP):
aerobic respiration [GO:0009060]; mitochondrial ATP synthesis coupled proton transport [GO:0042776]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]...
aerobic respiration [GO:0009060]; mitochondrial ATP synthesis coupled proton transport [GO:0042776]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]
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GO - Molecular function (MF):
NADH dehydrogenase (ubiquinone) activity [GO:0008137]...
NADH dehydrogenase (ubiquinone) activity [GO:0008137]
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GO - Cellular component (CC):
azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]...
azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]
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NDUFC2
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*NOTE: the Kaplan plots were collected from OncoLnc