DegronMD - O95382(MAP3K6)

MAP3K6

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F791C	TCGA-13-0920	OV	TCGA	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation rewiring degron network	0.0833
p.F791C	DO28099	OV	ICGC	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation rewiring degron network	0.0833
p.A798T	TCGA-A5-A1OF	UCEC	TCGA	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation rewiring degron network	0.2778
p.A798T	DO42568	UCEC	ICGC	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation rewiring degron network	0.2778
p.G792D	TCGA-DI-A1BU	UCEC	TCGA	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation rewiring degron network	0.1111
p.G792D	DO42023	UCEC	ICGC	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation rewiring degron network	0.1111
p.T806A	SIDM01287	Esophageal Carcinoma	GDSC	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation blocking phosphorylation signal	0.75
p.G809E	SIDM00516	Melanoma	GDSC	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation rewiring degron network	0.2222
p.G809E	MZ7-mel	skin	COSMIC	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation rewiring degron network	0.2222
p.G801E	MZ7-mel	skin	COSMIC	ITPCTE	DEG_SCF_FBW7_2	800:805	Mutation altering degron motif	0.7199

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*NOTE: the Kaplan plots were collected from OncoLnc