DegronMD - O95394(PGM3)

PGM3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D511Y	TCGA-AA-3984	COAD	TCGA	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.2778
p.D511Y	DO9002	COAD	ICGC	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.2778
p.K515R	TCGA-DI-A1BU	UCEC	TCGA	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.1667
p.K515R	DO42023	UCEC	ICGC	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.1667
p.G504V	TCGA-EO-A22R	UCEC	TCGA	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation altering degron motif	0.7532
p.D494V	TCGA-HP-A5N0	LIHC	TCGA	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.0556
p.R496W	DO233858	GACA	ICGC	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.1111
p.R496W	DO13522	GBM	ICGC	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.1111
p.V504I	DO233942	GACA	ICGC	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation altering degron motif	0.5965
p.H518N	DO229015	LICA	ICGC	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.0833
p.P503L	SIDM00296	Small Cell Lung Carcinoma	GDSC	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.3056
p.P503L	LU-134-A	lung	COSMIC	VRVYAE	LIG_APCC_ABBA_1	504:509	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc