DegronMD - O95865(DDAH2)

DDAH2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G238V	TCGA-A6-2686	COAD	TCGA	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1389
p.G238V	DO7828	COAD	ICGC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1389
p.A216T	TCGA-B5-A3FC	UCEC	TCGA	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1389
p.A216T	DO41871	UCEC	ICGC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1389
p.L223F	TCGA-FD-A43N	BLCA	TCGA	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation altering degron motif	0.587
p.L223F	DO502	BLCA	ICGC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation altering degron motif	0.587
p.C220S	TCGA-G3-A5SJ	LIHC	TCGA	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.25
p.C220S	DO44938	LIHC	ICGC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.25
p.G239V	DO225352	BRCA	ICGC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1111
p.D215G	DO232623	PBCA	ICGC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1111
p.R224C	SIDM00938	Breast Carcinoma	GDSC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation altering degron motif	0.8301
p.D215N	SIDM00381	Cervical Carcinoma	GDSC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1111
p.D215N	ACH-002020	Cervical Cancer	CCLE	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1111
p.D215N	SKG-IIIa	cervix	COSMIC	LRPGLPGVP	DEG_APCC_DBOX_1	223:231	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc