DegronMD - O95873(C6orf47)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R87I	TCGA-A5-A2K5	UCEC	TCGA	PISST	DEG_SPOP_SBC_1	96:100	Mutation rewiring degron network	0.0833
p.R87I	TCGA-EO-A3AV	UCEC	TCGA	PISST	DEG_SPOP_SBC_1	96:100	Mutation rewiring degron network	0.0833
p.R87I	DO52412	UCEC	ICGC	PISST	DEG_SPOP_SBC_1	96:100	Mutation rewiring degron network	0.0833
p.R87I	DO41379	UCEC	ICGC	PISST	DEG_SPOP_SBC_1	96:100	Mutation rewiring degron network	0.0833
p.S36W	TCGA-AC-A5XS	BRCA	TCGA	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation altering degron motif	0.8985
p.S36W	DO50023	BRCA	ICGC	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation altering degron motif	0.8985
p.E37D	TCGA-AG-A002	READ	TCGA	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.3056
p.S41C	TCGA-CJ-6030	KIRC	TCGA	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation blocking phosphorylation signal	0.6389
p.S41C	DO19058	KIRC	ICGC	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation blocking phosphorylation signal	0.6389
p.S41N	TCGA-EY-A1GU	UCEC	TCGA	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation blocking phosphorylation signal	0.6389
p.S41N	DO41518	UCEC	ICGC	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation blocking phosphorylation signal	0.6389
p.E37Q	TCGA-XF-AAMG	BLCA	TCGA	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.3056
p.E37Q	DO219049	BLCA	ICGC	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.3056
p.E37K	DO224732	BRCA	ICGC	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.3056
p.D89H	DO1954	BRCA	ICGC	PISST	DEG_SPOP_SBC_1	96:100	Mutation rewiring degron network	0.1389
p.K92N	DO234285	ESAD	ICGC	PISST	DEG_SPOP_SBC_1	96:100	Mutation substituting flanking lysine	0.3333
p.K92N	DO229505	LAML	ICGC	PISST	DEG_SPOP_SBC_1	96:100	Mutation substituting flanking lysine	0.3333
p.K92N	DO230527	LUSC	ICGC	PISST	DEG_SPOP_SBC_1	96:100	Mutation substituting flanking lysine	0.3333
p.K92N	DO52365	LUSC	ICGC	PISST	DEG_SPOP_SBC_1	96:100	Mutation substituting flanking lysine	0.3333
p.K92N	DO231120	LUSC	ICGC	PISST	DEG_SPOP_SBC_1	96:100	Mutation substituting flanking lysine	0.3333
p.R31W	DO233764	GACA	ICGC	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.3056
p.A46V	DO229211	THCA	ICGC	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.0556
p.P29A	SIDM00455	Pancreatic Carcinoma	GDSC	VDSSS	DEG_SPOP_SBC_1	32:36	Mutation rewiring degron network	0.25

DegronMD: protein-targeted degradation, mutation and drug response to degrons

C6orf47

UniProt ID: O95873

Entrez ID: 57827

Protein name: Uncharacterized protein C6orf47 (Protein G4)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for C6orf47 in