DegronMD - O95931(CBX7)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K77R	TCGA-19-1786	GBM	TCGA	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation altering degron motif	0.6126
p.K77R	DO11956	GBM	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation altering degron motif	0.6126
p.D88E	TCGA-66-2773	LUSC	TCGA	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.25
p.D88E	DO26536	LUSC	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.25
p.R78W	TCGA-AA-A01R	COAD	TCGA	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation altering degron motif	0.8634
p.R78W	DO7934	COAD	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation altering degron motif	0.8634
p.R72I	TCGA-D1-A17Q	UCEC	TCGA	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.1944
p.R72I	DO41903	UCEC	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.1944
p.G68W	TCGA-D9-A149	SKCM	TCGA	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.0833
p.G68W	DO37420	SKCM	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.0833
p.P74L	TCGA-FI-A2D0	UCEC	TCGA	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.25
p.P74L	DO43891	UCEC	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.25
p.R78Q	TCGA-FP-A4BE	STAD	TCGA	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation altering degron motif	0.7329
p.R78Q	DO48016	STAD	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation altering degron motif	0.7329
p.A93S	DO231776	LINC	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.1111
p.R90Q	DO227664	PBCA	ICGC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.1944
p.V89I	CCK-81	large intestine	COSMIC	KRLLLQRLY	DEG_APCC_DBOX_1	77:85	Mutation rewiring degron network	0.2222

Kaplan plot for CBX7 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CBX7

UniProt ID: O95931

Entrez ID: 23492

Protein name: Chromobox protein homolog 7

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for CBX7 in