DegronMD - O95992(CH25H)

CH25H

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A81T	TCGA-CK-5913	COAD	TCGA	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation rewiring degron network	0.1944
p.A81T	DO8826	COAD	ICGC	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation rewiring degron network	0.1944
p.S78L	TCGA-YC-A89H	BLCA	TCGA	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation rewiring degron network	0.2778
p.S78L	DO51948	BLCA	ICGC	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation rewiring degron network	0.2778
p.W64C	DO228935	COCA	ICGC	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation rewiring degron network	0.1667
p.H74N	DO229008	LICA	ICGC	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation altering degron motif	0.7423
p.P86L	SIDM01006	Plasma Cell Myeloma	GDSC	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation rewiring degron network	0.0556
p.P86L	KARPAS-620	haematopoietic and lymphoid tissue	COSMIC	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation rewiring degron network	0.0556
p.R70H	SIDM00251	Gastric Carcinoma	GDSC	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation altering degron motif	0.8244
p.R70H	ACH-000949	Gastric Cancer	CCLE	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation altering degron motif	0.8244
p.R70H	TGBC11TKB	stomach	COSMIC	RYKIHPD	LIG_APCC_ABBAyCdc20_2	70:76	Mutation altering degron motif	0.8244

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*NOTE: the Kaplan plots were collected from OncoLnc