DegronMD - O96011(PEX11B)

PEX11B

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R137C	TCGA-D1-A174	UCEC	TCGA	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.1944
p.A120T	TCGA-EE-A2MR	SKCM	TCGA	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.2222
p.V114M	TCGA-G4-6302	COAD	TCGA	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.0556
p.S137F	DO465	BLCA	ICGC	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.1944
p.M132V	DO5417	BRCA	ICGC	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation altering degron motif	0.7208
p.M133V	DO231945	LICA	ICGC	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.3056
p.F124Y	DO229229	THCA	ICGC	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation altering degron motif	0.6417
p.R123C	DO40900	UCEC	ICGC	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.3056
p.A120V	SIDM00932	Kidney Carcinoma	GDSC	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.2222
p.A120V	ACH-000457	Kidney Cancer	CCLE	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.2222
p.A120V	CAL-54	kidney	COSMIC	FRYYLFSLI	DEG_APCC_DBOX_1	124:132	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc