DegronMD - P00797(REN)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R43Q	TCGA-55-A48Y	LUAD	TCGA	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.R43Q	TCGA-DA-A1IC	SKCM	TCGA	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.R43Q	DO26160	LUAD	ICGC	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.R43Q	DO37430	SKCM	ICGC	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.R43Q	SIDM00562	Breast Carcinoma	GDSC	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.R43Q	ACH-002163	Breast Cancer	CCLE	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.R43Q	MRK-nu-1	breast	COSMIC	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.T29A	TCGA-EO-A22R	UCEC	TCGA	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.T29A	DO42713	UCEC	ICGC	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.R49L	TCGA-G2-A2EJ	BLCA	TCGA	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.0833
p.R49L	DO554	BLCA	ICGC	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.0833
p.R43P	TCGA-Q1-A5R3	CESC	TCGA	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.R43P	DO49008	CESC	ICGC	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.25
p.E48K	DO27869	ORCA	ICGC	KRIFLKRMP	DEG_APCC_DBOX_1	32:40	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons